Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921567 | 0.91 | SMN1; SMN2 (0.47) | CTSKAPPMAPTAKT1CYP1A2 | |
| SCHEMBL8921583 | 0.88 | MAPT (0.48) | CTSKAPPMAPTAKT1CTSS | |
| SCHEMBL8921588 | 0.86 | CTSK (0.41) | CTSKAPPMAPTAKT1CYP1A2 | |
| SCHEMBL8921748 | 0.86 | CTSK (0.41) | CTSKAPPMAPTAKT1CYP1A2 | |
| SCHEMBL8921597 | 0.86 | CTSK (0.41) | CTSKAPPMAPTAKT1CYP1A2 | |
| SCHEMBL8921737 | 0.86 | CTSK (0.41) | CTSKAPPMAPTAKT1CYP1A2 | |
| SCHEMBL8923100 | 0.86 | AKT1 (0.46) | CTSKAKT1 | |
| SCHEMBL8921589 | 0.86 | AKT1 (0.46) | CTSKAKT1 | |
| SCHEMBL8920403 | 0.86 | AKT1 (0.46) | CTSKAKT1 | |
| SCHEMBL8920576 | 0.83 | CTSS (0.50) | CTSKAKT1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |