Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920052 | 0.84 | KMT2A (0.53) | MEN1RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8921220 | 0.76 | MCHR1 (0.30) | — | |
| SCHEMBL8707234 | 0.75 | HRH3 (0.37) | KDM4EPTPN1 | |
| SCHEMBL8712010 | 0.73 | CYP1A1 (0.38) | MEN1RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8705669 | 0.68 | ACACB (0.39) | KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8772744 | 0.68 | MMP13 (0.56) | — | |
| SCHEMBL10584963 | 0.67 | CA12 (0.54) | MEN1RAB9AKMT2ANPC1CA12 | |
| SCHEMBL8574139 | 0.66 | CHRNA7 (0.50) | CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL8421972 | 0.66 | ACACB (0.38) | — | |
| SCHEMBL5785443 | 0.65 | HDAC1 (0.69) | MEN1RAB9AKMT2ANPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |