Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.49 |
| ▸ | CTSS | P25774 | 9/20 | 0.49 |
| ▸ | CTSL | P07711 | 8/20 | 0.49 |
| ▸ | CTSB | P07858 | 6/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921733 | 1.00 | CTSK (0.49) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL8122104 | 0.92 | CTSK (0.48) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL6841176 | 0.80 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL7422252 | 0.80 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL27926954 | 0.80 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL10108119 | 0.79 | CTSK (0.55) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL8609108 | 0.77 | CTSK (0.46) | CTSKCTSSCTSLCTSBACE2 | |
| SCHEMBL8609103 | 0.77 | CTSK (0.46) | CTSKCTSSCTSLCTSBACE2 | |
| SCHEMBL13572927 | 0.76 | ATM (0.59) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL6407665 | 0.76 | ATM (0.59) | CTSKCTSSCTSLCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616620-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-04-01 | — | — | US | disclosed |