Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSS | P25774 | 7/20 | 0.48 |
| ▸ | CTSL | P07711 | 6/20 | 0.48 |
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921739 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL8921733 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL7422252 | 0.79 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL6841176 | 0.79 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL27926954 | 0.79 | CTSK (0.67) | CTSKCTSSCTSLCTSBATM | |
| SCHEMBL10201895 | 0.78 | MIF (0.46) | CTSKCTSSCTSLKYNUKMT2A | |
| SCHEMBL8609103 | 0.78 | CTSK (0.46) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL8609108 | 0.78 | CTSK (0.46) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL8119475 | 0.78 | HTT (0.54) | LMNA | |
| SCHEMBL820965 | 0.76 | MIF (0.56) | ATMMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |