SCHEMBL8921986

SCHEMBL8921986

COC(=O)CCNC(=O)c1cc(I)ccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7334498 0.88 CYP1A2 (0.39) MAPTSMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL17556530 0.86 CCR2 (0.44) MAPTSMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL7329535 0.84 CA1 (0.42) CA1CA2ALDH1A1HPGDKDM4E
SCHEMBL7104333 0.82 L3MBTL1 (0.48) ALDH1A1HPGDKDM4EHSD17B10GAA
SCHEMBL7328344 0.81 HRH4 (0.42) SMN1; SMN2ALDH1A1MAPK1
SCHEMBL13753892 0.79 NOS2 (0.43) MAPTCA2CA4ALDH1A1HPGD
SCHEMBL8151587 0.79 CA1 (0.46) CA12CA1CA2CA3CA4
SCHEMBL7795525 0.77 CYP1A2 (0.39) MAPTSMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL8923896 0.77 NR1H4 (0.43) MAPTSMN1; SMN2NR1H4ALDH1A1HPGD
SCHEMBL8922059 0.77 HPGD (0.44) MAPTSMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693637-A Bicycle derivatives, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed