Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPRE | P23469 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921986 | 0.77 | MAPT (0.41) | NR1H4HSD17B10HPGDALDH1A1MAPT | |
| SCHEMBL6012277 | 0.75 | ALDH1A1 (0.51) | HSD17B10HPGDALDH1A1MAPTPTPRC | |
| SCHEMBL7323307 | 0.73 | CYP1A2 (0.39) | HPGDALDH1A1MAPTSMN1; SMN2MAP2K2 | |
| SCHEMBL16651569 | 0.71 | KMT2A (0.53) | HSD17B10HPGDALDH1A1MAPTPTPRC | |
| SCHEMBL8959409 | 0.70 | NPSR1 (0.40) | NR1H4PTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL31113419 | 0.70 | CCR2 (0.42) | HSD17B10HPGDPTPRCPTPN2PTPN1 | |
| SCHEMBL16662129 | 0.69 | HTT (0.43) | HSD17B10HPGDALDH1A1MAPTPTPRC | |
| SCHEMBL7322908 | 0.69 | PTGS2 (0.43) | HSD17B10HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7322396 | 0.69 | ALDH1A1 (0.45) | HSD17B10ALDH1A1MAPTPOLB | |
| SCHEMBL8836859 | 0.68 | CYP3A4 (0.41) | ALDH1A1PTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693637-A | Bicycle derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |