Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023978 | 0.84 | ALDH1A1 (0.49) | LMNAALDH1A1GAAHTTHSD17B10 | |
| SCHEMBL11427621 | 0.84 | L3MBTL1 (0.49) | LMNAALDH1A1CTSLCTSBKMT2A | |
| SCHEMBL11449287 | 0.79 | ALOX5 (0.52) | LMNAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL5962623 | 0.79 | CYP4F2 (0.50) | ALDH1A1GAAHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL8923083 | 0.79 | TSHR (0.45) | HSD17B10SMN1; SMN2MAPTTSHR | |
| SCHEMBL4423244 | 0.77 | CYP4F2 (0.57) | LMNAALDH1A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL11369770 | 0.75 | ALDH1A1 (0.57) | LMNAALDH1A1GAAHTTHSD17B10 | |
| SCHEMBL8863393 | 0.73 | SMN1; SMN2 (0.46) | LMNAGAAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL1710113 | 0.72 | CES1 (0.50) | LMNAALDH1A1GAAHTTHSD17B10 | |
| SCHEMBL20841661 | 0.72 | MGAM (0.52) | LMNAALDH1A1GAAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |