Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916036 | 0.82 | HPGD (0.38) | ALDH1A1ADRB2ADRB3TSHRLMNA | |
| SCHEMBL5256681 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP3A4L3MBTL1NPC1 | |
| SCHEMBL7501045 | 0.81 | LMNA (0.35) | TP53CYP3A4TSHRNPC1LMNA | |
| SCHEMBL778445 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1TSHRPOLB | |
| SCHEMBL7117001 | 0.79 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL917313 | 0.78 | NPSR1 (0.46) | ALDH1A1L3MBTL1TSHRLMNA | |
| SCHEMBL1629454 | 0.77 | ALOX5 (0.34) | ALDH1A1KDM4ETP53POLB | |
| SCHEMBL6118428 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP3A4FBP1L3MBTL1LMNA | |
| SCHEMBL7528685 | 0.76 | ADAMTS4 (0.37) | FBP1 | |
| SCHEMBL16146502 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4ETP53CYP3A4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |