Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778445 | 0.83 | ALDH1A1 (0.47) | TSHRKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL3894262 | 0.75 | TSHR (0.47) | TSHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7501045 | 0.74 | LMNA (0.35) | CYP2C19TSHRLMNATDP1SMN1; SMN2 | |
| SCHEMBL11648928 | 0.74 | MEN1 (0.39) | CYP2C19KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL914853 | 0.74 | HTT (0.39) | ALDH1A1LMNAMAPTHPGDKMT2A | |
| SCHEMBL895237 | 0.74 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL14809659 | 0.72 | NPC1 (0.40) | CNR2ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL8922170 | 0.72 | CYP2C19 (0.53) | CYP2C19TSHRKDM4ENR3C1CRHBP | |
| SCHEMBL1407856 | 0.71 | TRPA1 (0.42) | TSHRHPGDKMT2A | |
| SCHEMBL10778766 | 0.70 | CYP2C19 (0.54) | CYP2C19TSHRKDM4ENR3C1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |