Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925600 | 0.82 | CCNE1 (0.37) | PPARAALDH1A1USP2TYK2 | |
| SCHEMBL8992121 | 0.75 | BRD4 (0.37) | NR1I2CYP3A4CYP2D6PPARANPC1 | |
| SCHEMBL8557109 | 0.74 | KMT2A (0.36) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8603712 | 0.74 | NR1I2 (0.37) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8553780 | 0.72 | NPC1 (0.36) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL9090966 | 0.72 | NR1I2 (0.34) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8665035 | 0.72 | RIPK1 (0.34) | PPARAALDH1A1USP2KDM4EMAPT | |
| SCHEMBL8605399 | 0.71 | NR1I2 (0.36) | NR1I2CYP3A4CYP2D6NPC1NFKB1 | |
| SCHEMBL8924461 | 0.71 | NPC1 (0.33) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL9078729 | 0.71 | RAB9A (0.41) | NR1I2CYP3A4CYP2D6NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |