Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922280 | 0.91 | ALDH1A1 (0.47) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL9789474 | 0.89 | RAB9A (0.64) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL28438378 | 0.84 | NPC1 (0.53) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL10587731 | 0.82 | ALDH1A1 (0.55) | MAPTNPC1RAB9ASRD5A2ALDH1A1 | |
| SCHEMBL1700802 | 0.81 | SRD5A2 (0.72) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL28380464 | 0.79 | AHR (0.42) | MAPTNPC1RAB9AKDM4E | |
| SCHEMBL28387896 | 0.79 | CRBN (0.42) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL28432070 | 0.79 | NPC1 (0.49) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL6901141 | 0.79 | SRD5A2 (0.66) | MAPTNPC1RAB9ASRD5A2HSD17B1 | |
| SCHEMBL18585497 | 0.78 | ALDH1A1 (0.68) | MAPTNPC1RAB9AALDH1A1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |