Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922280 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL18585497 | 0.91 | ALDH1A1 (0.68) | ALDH1A1RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL6582499 | 0.91 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL9255205 | 0.86 | HTR2C (0.53) | ALDH1A1MELK | |
| SCHEMBL11806865 | 0.84 | SRD5A2 (0.59) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL8922273 | 0.82 | MAPT (0.50) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL9789474 | 0.80 | RAB9A (0.64) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL28554091 | 0.79 | PIR (0.41) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL9477896 | 0.79 | ALDH1A1 (0.83) | ALDH1A1SRD5A1SRD5A2RAB9ANPC1 | |
| SCHEMBL9944563 | 0.78 | CASP1 (0.52) | SRD5A1SRD5A2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323536-A1 | Arylcyclobutene/dienophile copolymers | THE DOW CHEMICAL COMPANY (US) | 1989-07-12 | — | — | EP | disclosed |