Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922273 | 0.91 | MAPT (0.50) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL10587731 | 0.91 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL9789474 | 0.85 | RAB9A (0.64) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL18585497 | 0.83 | ALDH1A1 (0.68) | ALDH1A1NPC1RAB9AMAPTCTNNB1 | |
| SCHEMBL6582499 | 0.83 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMAPTCTNNB1 | |
| SCHEMBL11806865 | 0.81 | SRD5A2 (0.59) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL28438378 | 0.80 | NPC1 (0.53) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL9255205 | 0.79 | HTR2C (0.53) | ALDH1A1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL1700802 | 0.77 | SRD5A2 (0.72) | ALDH1A1NPC1RAB9AMAPTSRD5A2 | |
| SCHEMBL28380464 | 0.76 | AHR (0.42) | NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |