Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919946 | 0.84 | MMP12 (0.45) | ACEMMP12CTSKCTSLCTSB | |
| SCHEMBL8921955 | 0.81 | MMP12 (0.43) | ACEMMP12CTSKCTSLCTSB | |
| SCHEMBL1114427 | 0.81 | CPA3 (0.54) | MMP12CTSKSLC7A5ALDH1A1ALPI | |
| SCHEMBL8919952 | 0.78 | MMP12 (0.45) | ACEMMP12CTSKCTSLCTSB | |
| SCHEMBL8922524 | 0.78 | CTSK (0.40) | ACEMMP12CTSKCTSLCTSB | |
| SCHEMBL2289952 | 0.76 | CTSK (0.56) | MMP12CTSKCTSLCTSBSLC7A5 | |
| SCHEMBL12378816 | 0.76 | CTSK (0.56) | MMP12CTSKCTSLCTSBSLC7A5 | |
| SCHEMBL8811765 | 0.76 | MMP12 (0.48) | MMP12CTSKCTSLCTSBSLC7A5 | |
| SCHEMBL8922511 | 0.73 | PPARA (0.42) | ACEATMMMP12CTSKCTSS | |
| SCHEMBL3008826 | 0.73 | CTSK (0.56) | MMP12CTSKCTSLCTSBSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |