Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114427 | 0.82 | CPA3 (0.54) | CTSKMMP12FOLH1LTA4HALDH1A1 | |
| SCHEMBL8919952 | 0.79 | MMP12 (0.45) | CTSKMMP12CTSLCTSBFOLH1 | |
| SCHEMBL8919946 | 0.79 | MMP12 (0.45) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL8922517 | 0.78 | ACE (0.42) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL8811765 | 0.77 | MMP12 (0.48) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL12378816 | 0.77 | CTSK (0.56) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL2289952 | 0.77 | CTSK (0.56) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL8921955 | 0.77 | MMP12 (0.43) | CTSKMMP12CTSLCTSBALDH1A1 | |
| SCHEMBL8204879 | 0.76 | CTSK (0.53) | CTSKMMP12CTSLCTSBLTA4H | |
| SCHEMBL19304566 | 0.76 | ANPEP (0.45) | CTSKMMP12CTSLCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |