Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 6/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947775 | 0.94 | NAAA (0.49) | NAAAALOX5PRKCADGKATSHR | |
| SCHEMBL22642652 | 0.87 | PRKCA (0.47) | NAAAALOX5PRKCADGKA | |
| SCHEMBL18970778 | 0.84 | PRKCA (0.46) | NAAAALOX5PRKCADGKA | |
| SCHEMBL11284017 | 0.83 | NAAA (0.58) | NAAAALOX5PRKCADGKALMNA | |
| SCHEMBL4941578 | 0.80 | NAAA (0.68) | NAAAPRKCADGKALMNAPAM | |
| SCHEMBL30947774 | 0.80 | ALOX5 (0.38) | NAAAALOX5PRKCA | |
| SCHEMBL22920283 | 0.80 | PRKCA (0.42) | NAAAALOX5PRKCADGKATSHR | |
| SCHEMBL2505317 | 0.78 | ALOX5 (0.62) | NAAAALOX5DGKATSHRLMNA | |
| SCHEMBL16174233 | 0.78 | ALOX5 (0.62) | NAAAALOX5DGKATSHRLMNA | |
| SCHEMBL10085305 | 0.78 | ALOX5 (0.62) | NAAAALOX5DGKATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679801-A | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |