Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | STK4 | Q13043 | 2/20 | 0.49 |
| ▸ | STK3 | Q13188 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922043 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8920563 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8922167 | 0.87 | HSD17B10 (0.57) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8923242 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8921644 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10ALOX15AKR1C3 | |
| SCHEMBL8921982 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8921416 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10ALOX15USP2 | |
| SCHEMBL8923442 | 0.84 | ALDH1A1 (0.83) | ALDH1A1HPGDHSD17B10ALOX15STK4 | |
| SCHEMBL8921343 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10ALOX15KDM4E | |
| SCHEMBL9858078 | 0.81 | STK4 (0.55) | ALDH1A1HPGDHSD17B10ALOX15STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | claimed |
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |