Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.59 |
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | RARG | P13631 | 5/20 | 0.59 |
| ▸ | RXRA | P19793 | 5/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467739 | 0.91 | PTGS2 (0.57) | RARARARBRARGRXRAPTGS2 | |
| SCHEMBL8925466 | 0.90 | PTGS2 (0.59) | RARARARBRARGRXRAPTGS2 | |
| SCHEMBL27342072 | 0.87 | ALOX5 (0.61) | PTGS2ALOX5CYP2C9PTGS1 | |
| SCHEMBL7459996 | 0.86 | PTGS2 (0.62) | PTGS2ALOX5CYP2C9PTGS1 | |
| SCHEMBL9203630 | 0.86 | PTGS2 (0.65) | PTGS2ALOX5CYP2C9PTGS1 | |
| SCHEMBL9201549 | 0.85 | PTGS2 (0.78) | PTGS2ALOX5AOC3CYP2C9PTGS1 | |
| SCHEMBL9207728 | 0.85 | PTGS2 (0.64) | PTGS2ALOX5AOC3CYP2C9PTGS1 | |
| SCHEMBL9203156 | 0.85 | PTGS2 (0.78) | PTGS2ALOX5AOC3CYP2C9PTGS1 | |
| SCHEMBL9210069 | 0.84 | PTGS2 (0.60) | PTGS2ALOX5PTGS1 | |
| SCHEMBL9209927 | 0.84 | AOC3 (0.60) | PTGS2ALOX5AOC3CYP2C9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670533-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIRHEUMATIC DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5550147-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTITHROMBOTIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0554829-A2 | Pyrazole derivatives with antiinflammatory, analgesic and antithrombolic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |