Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687253 | 0.90 | ALDH1A1 (0.46) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL8923582 | 0.84 | LMNA (0.48) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL4687415 | 0.83 | LMNA (0.47) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL4684141 | 0.82 | ALDH1A1 (0.37) | LMNAALDH1A1HTTGAA | |
| SCHEMBL5663959 | 0.81 | CA2 (0.50) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL4687250 | 0.81 | LMNA (0.46) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL1258986 | 0.80 | STAT3 (0.47) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11880300 | 0.79 | RECQL (0.46) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL11880309 | 0.79 | RECQL (0.46) | LMNATDP1ALDH1A1HTTPKM | |
| SCHEMBL5501025 | 0.79 | RECQL (0.46) | LMNATDP1ALDH1A1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |