Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490265 | 0.83 | CHRNA7 (0.31) | NR1I2ALDH1A1CHRNA7POLB | |
| SCHEMBL8924477 | 0.72 | CYP2D6 (0.32) | — | |
| SCHEMBL27464474 | 0.69 | NR1I2 (0.39) | NR1I2KDM4EALDH1A1CHRNA7POLB | |
| SCHEMBL8924535 | 0.68 | GSK3B (0.30) | — | |
| SCHEMBL8496732 | 0.66 | CHRNA7 (0.42) | NR1I2GAACHRNA7PDE4APDE4B | |
| SCHEMBL28581938 | 0.66 | NR1I2 (0.44) | NR1I2GAAKDM4EALDH1A1CHRNA7 | |
| SCHEMBL9379275 | 0.66 | POLB (0.30) | POLB | |
| SCHEMBL8923397 | 0.66 | MEN1 (0.33) | GAA | |
| SCHEMBL5997170 | 0.64 | MGLL (0.45) | GAAALDH1A1 | |
| SCHEMBL5605046 | 0.63 | HPGD (0.46) | NR1I2GAAALDH1A1CHRNA7PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684151-A | PROGESTIN AGONISTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0650480-A1 | 1-ARYLSULPHONYL, ARYLCARBONYL AND 1-ARYLPHOSPHONYL-3-PHENYL-1,4,5,6-TETRAHYDROPYRIDAZINES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001412-A1 | 1-ARYLSULPHONYL, ARYLCARBONYL AND 1-ARYLPHOSPHONYL-3-PHENYL-1,4,5,6-TETRAHYDROPYRIDAZINES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-01-20 | — | — | WO | disclosed |