SCHEMBL5997170

SCHEMBL5997170

COc1ccccc1N1N=CCCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.45
HTR7 P34969 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
HTR1A P08908 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PTGS1 P23219 2/20 0.43
PTGS2 P35354 2/20 0.43
GAA P10253 1/20 0.43
CASP3 P42574 1/20 0.43
CASP6 P55212 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
MAPT P10636 2/20 0.42
METAP2 P50579 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9462156 0.78 L3MBTL1 (0.42) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL10618445 0.72 POLB (0.46) MEN1KMT2ACYP1A2PTGS1PTGS2
SCHEMBL5309397 0.72 ALOX5 (0.48) MGLLCYP1A2MAPTSMN1; SMN2
SCHEMBL4661873 0.71 MAPT (0.57) MGLLMEN1KMT2ACYP1A2PTGS1
SCHEMBL8152227 0.69 ATM (0.52) MGLLHTR7MEN1KMT2ACYP1A2
SCHEMBL20703098 0.69 TUBB4A (0.37) PTGS1PTGS2MAPTALDH1A1
SCHEMBL1829260 0.67 MAPT (0.58) MGLLHTR7MEN1KMT2ACYP1A2
SCHEMBL3534430 0.67 GAA (0.43) MGLLHTR7MEN1KMT2APTGS1
SCHEMBL10754981 0.66
SCHEMBL8115164 0.66 GAA (0.63) MGLLHTR7MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122198-B1 Fast dissolving composition with prolonged sweet taste PANACEA BIOTEC LIMITED (IN) 2006-10-17 US disclosed
US-5719197-A DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 1998-02-17 US disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed
US-5204463-A Substituted methoxyphenyl-4,5 dihydro-3(2H)-pridazinones having cardiotonic and beta blocking activities GLAXO INC. (US) 1993-04-20 US disclosed