Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923783 | 0.84 | GFER (0.42) | KCNH2NPSR1HSD17B10 | |
| SCHEMBL9038015 | 0.84 | ALDH1A1 (0.47) | KCNH2NPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9001495 | 0.83 | ALDH1A1 (0.46) | KCNH2NPSR1HSD17B10 | |
| SCHEMBL9037637 | 0.83 | GFER (0.56) | NPSR1 | |
| SCHEMBL8985883 | 0.82 | ALDH1A1 (0.50) | NPSR1HSD17B10 | |
| SCHEMBL9539611 | 0.82 | ADRA2A (0.51) | TRPV1KCNH2 | |
| Hydrochloric Acid SCHEMBL8985797 | 0.82 | ALDH1A1 (0.49) | NPSR1HSD17B10 | |
| SCHEMBL8922978 | 0.81 | TNFSF11 (0.57) | TRPV1 | |
| SCHEMBL9038498 | 0.79 | ADRA2A (0.55) | TRPV1KCNH2HSD17B10 | |
| SCHEMBL8923192 | 0.78 | ADRA2A (0.52) | TRPV1KCNH2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | claimed |