Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422682 | 0.81 | — | — | |
| SCHEMBL733409 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL29285237 | 0.77 | — | — | |
| SCHEMBL22652 | 0.75 | — | — | |
| SCHEMBL413500 | 0.75 | — | — | |
| SCHEMBL2180334 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL10935262 | 0.75 | — | — | |
| SCHEMBL4886947 | 0.75 | — | — | |
| Water SCHEMBL6908198 | 0.75 | LPAR3 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL497349 | 0.75 | P2RY14 (0.34) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994019363-A1 | PROCESS FOR PREPARING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |