SCHEMBL2180334

SCHEMBL2180334

N#CCCOP(N)(=O)OCCC#N

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LOX P28300 1/20 0.33
LOXL3 P58215 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10935262 0.85
SCHEMBL5485766 0.83
SCHEMBL28992261 0.80
SCHEMBL733409 0.79 ALDH1A1 (0.43) ALDH1A1TDP1LOXLOXL3LOXL2
SCHEMBL29285237 0.77
SCHEMBL22652 0.75
SCHEMBL8923972 0.75 ALDH1A1 (0.33) ALDH1A1TDP1
Water SCHEMBL6908198 0.75 LPAR3 (0.41) ALDH1A1TDP1
SCHEMBL413500 0.75
SCHEMBL4886947 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111578-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. (US) 2025-05-30 WO claimed
WO-2025111578-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. (US) 2025-05-30 WO disclosed
CN-112426538-A micro-RNAs and compositions comprising micro-RNAs 耶达研究及发展有限公司 2021-03-02 CN disclosed
CN-112055749-A Use of FUBP1 inhibitors for the treatment of hepatitis B virus infection 豪夫迈·罗氏有限公司 2020-12-08 CN disclosed
CN-107115352-B micro-RNAs and compositions comprising micro-RNAs 耶达研究及发展有限公司 2020-10-30 CN disclosed
CN-110291104-A Compounds having anti-tumor activity against cancer cells carrying an EGFR or HER2 exon 20 mutation 得克萨斯州大学系统董事会 2019-09-27 CN disclosed
CN-107988227-A Efficient nanoparticle form double helix widow RNA structures and preparation method thereof 株式会社百奥尼 2018-05-04 CN disclosed
CN-105705639-A Dengue virus-specific sirna, double helix oligo-rna structure comprising sirna, and composition for suppressing proliferation of dengue virus comprising rna structure 柏业公司 2016-06-22 CN disclosed
CN-104114704-A High-efficiency nanoparticle-type double-helix oligo-RNA structure and preparation method thereof BIONEER CORP 2014-10-22 CN disclosed
US-20110166043-A1 BIOMARKER DETECTION-2 ATERIS TECHNOLOGIES, LLC 2011-07-07 US disclosed
CN-1075336-A Novel biological process for the preparation of 7-ADCA MERCK & CO INC (US) 1993-08-18 CN disclosed
CN-1074484-A The new biological method of preparation 7-ACA and 7-ADAC MERCK & CO INC (US) 1993-07-21 CN disclosed
EP-0538404-A4 FIBROBLAST GROWTH FACTOR RECEPTORS 1993-05-26 EP disclosed
EP-0538404-A1 FIBROBLAST GROWTH FACTOR RECEPTORS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1993-04-28 EP disclosed
CN-1062169-A PICHIA PASTORIS ACID PHOSPHATAE GENE PHILLIPS PETROLEUM CO (US) 1992-06-24 CN disclosed
WO-1992000999-A1 FIBROBLAST GROWTH FACTOR RECEPTORS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-01-23 WO disclosed
CN-1050044-A As vaccine or be used for the treatment of the defective hepatitis virus of liver disease UNIV YALE (US) 1991-03-20 CN disclosed
CN-1040053-A S before the expression hepatitis B in methylotrophic yeast 2Albumen PHILLIPS PETROLEUM CO (US) 1990-02-28 CN disclosed
CN-1039616-A PICHIA PASTORIS ALCOHOL OXIDASE II REGULATORY REGION PHILLIPS PETROLEUM CO (US) 1990-02-14 CN disclosed
CN-1038668-A In methylotrophic yeasts, express hepatitis B S and pre-s2 protein PHILLIPS PETROLEUM CO (US) 1990-01-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166043-A1 BIOMARKER DETECTION-2 CPB2, NAALAD2, PRSS2 ALDH1A1 1052/4885TDP1 2173/4885LOX 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.