Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684137 | 0.84 | KDM4E (0.32) | LMNATDP1ALDH1A1CYP19A1KDM4E | |
| SCHEMBL8923981 | 0.82 | ALDH1A1 (0.36) | LMNATDP1ALDH1A1CYP19A1MAPK1 | |
| SCHEMBL4686793 | 0.82 | TSHR (0.33) | LMNATDP1ALDH1A1CYP19A1KMT2A | |
| SCHEMBL4684141 | 0.79 | ALDH1A1 (0.37) | LMNAALDH1A1MAPK1GAA | |
| SCHEMBL27341025 | 0.76 | LMNA (0.35) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL28866557 | 0.74 | LMNA (0.34) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL17256433 | 0.72 | GAA (0.50) | LMNAALDH1A1KMT2AMAPK1GAA | |
| SCHEMBL9001244 | 0.69 | GAA (0.43) | LMNATDP1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8937977 | 0.67 | LMNA (0.39) | LMNATDP1ALDH1A1CYP19A1KMT2A | |
| SCHEMBL15041660 | 0.67 | LMNA (0.39) | LMNATDP1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |