Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491527 | 0.66 | — | — | |
| SCHEMBL8924542 | 0.60 | ALDH1A1 (0.33) | KMT2ANPC1RAB9AHSD17B10 | |
| SCHEMBL275597 | 0.56 | LMNA (0.79) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL5313046 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL21647917 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL165161 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL255601 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 | |
| SCHEMBL275598 | 0.53 | LMNA (0.64) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL29777368 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 | |
| Mandelic Acid SCHEMBL1050 | 0.53 | LMNA (1.00) | LMNAMAPK1POLBPKMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |