Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888162 | 0.78 | PDE4A (0.57) | — | |
| SCHEMBL22381391 | 0.73 | PGR (0.62) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8924157 | 0.72 | IDO1 (0.44) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29379840 | 0.72 | IDO1 (0.44) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29010554 | 0.72 | IDO1 (0.50) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26464505 | 0.69 | CYP11B1 (0.58) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11647726 | 0.68 | NFKB1 (0.54) | BLMNPSR1ALOX15ALOX12NFKB1 | |
| SCHEMBL27183350 | 0.67 | IDO1 (0.48) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27619310 | 0.66 | ALOX5 (0.57) | IDO1TUBB1KMT2AMEN1MAPT | |
| SCHEMBL14283825 | 0.66 | TYR (0.56) | TUBB1KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622977-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-22 | — | — | US | disclosed |