Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22381391 | 0.84 | PGR (0.62) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27183350 | 0.78 | IDO1 (0.48) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27619310 | 0.77 | ALOX5 (0.57) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10873515 | 0.76 | ERN1 (0.58) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5724135 | 0.75 | PARP1 (0.56) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20928116 | 0.75 | SLC6A3 (0.62) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28978917 | 0.74 | TLR8 (0.51) | TDP1TP53ARAPP | |
| SCHEMBL23202596 | 0.73 | TUBB4A (0.55) | MEN1KMT2ATUBB1TUBB4ATUBB | |
| SCHEMBL31079358 | 0.73 | TUBB4A (0.55) | MEN1KMT2ATUBB1TUBB4ATUBB | |
| SCHEMBL4681449 | 0.73 | ALDH1A1 (0.53) | IDO1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415329-B | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116042742-A | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-109415329-B | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-116042742-A | Synthesis method | 葛兰素史克知识产权第二有限公司 | 2023-05-02 | — | — | CN | disclosed |