Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127323 | 0.65 | SIGMAR1 (0.35) | SIGMAR1MAOAMAOBCYP3A4HSD17B10 | |
| SCHEMBL7118233 | 0.64 | POLB (0.34) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL17627642 | 0.60 | GAA (0.35) | NPSR1ALDH1A1 | |
| SCHEMBL17843655 | 0.60 | MAOA (0.35) | MTNR1AMTNR1BMAOAMAOB | |
| SCHEMBL7122632 | 0.60 | MAOA (0.36) | SIGMAR1MAOAMAOBNPSR1ALDH1A1 | |
| SCHEMBL29127913 | 0.58 | SIGMAR1 (0.38) | TP53MDM2SIGMAR1 | |
| SCHEMBL11556904 | 0.58 | MAOA (0.49) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL4442002 | 0.58 | MAOA (0.45) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL14181687 | 0.58 | ALDH1A1 (0.47) | MTNR1AMTNR1BMAOAMAOBCYP3A4 | |
| SCHEMBL7117159 | 0.57 | HTR2A (0.38) | MTNR1AMTNR1BMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020802-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | disclosed |