Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645150 | 0.83 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2HCAR2LMNA | |
| SCHEMBL4912310 | 0.81 | MGLL (0.55) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL2083526 | 0.78 | CTSK (0.53) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL4672346 | 0.77 | HCAR2 (0.67) | NPC1RAB9ASMN1; SMN2HCAR2AKR1B10 | |
| SCHEMBL7356625 | 0.77 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL9293730 | 0.77 | MGLL (0.55) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL23630606 | 0.77 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL12890310 | 0.77 | CTSK (0.59) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| SCHEMBL5931114 | 0.77 | MGLL (0.51) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 | |
| Phenethyl Phenylcarbamate SCHEMBL1835027 | 0.76 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2RECQLHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |