Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | KDM5C | P41229 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355639 | 0.84 | KDM4E (0.39) | KDM4ECA1CA2L3MBTL1 | |
| SCHEMBL18301257 | 0.76 | PRSS1 (0.36) | — | |
| SCHEMBL6196417 | 0.75 | GABRP (0.38) | LMNAKDM4EKDM4CKDM6BKDM5C | |
| SCHEMBL8924569 | 0.72 | GABRP (0.39) | LMNAKDM4EKDM4CKDM6BKDM5C | |
| SCHEMBL8924560 | 0.71 | GABRP (0.47) | LMNAKDM4EKDM4CKDM6BKDM5C | |
| SCHEMBL4160374 | 0.67 | PARP10 (0.42) | LMNACA1CA2ALDH1A1CA12 | |
| SCHEMBL2265942 | 0.64 | HPGD (0.34) | LMNAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL16475154 | 0.63 | LMNA (0.47) | LMNAKDM4EKDM4CKDM6BKDM5C | |
| SCHEMBL2241390 | 0.63 | MAPT (0.47) | KDM4EKDM4CCA1CA2ALDH1A1 | |
| SCHEMBL15843715 | 0.63 | KMO (0.46) | LMNAKDM4EKDM4CKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |