Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889155 | 0.86 | ALDH1A1 (0.45) | DGKALTA4HALDH1A1GLAPAOX | |
| SCHEMBL8851605 | 0.80 | GAA (0.52) | LTA4HALDH1A1PAOXTOP2AMAPT | |
| SCHEMBL12792361 | 0.80 | NAAA (0.58) | DGKADNM1HTR2CPRSS1PRSS2 | |
| SCHEMBL12792310 | 0.80 | NAAA (0.58) | DGKADNM1HTR2CPRSS1PRSS2 | |
| SCHEMBL128904 | 0.80 | — | — | |
| SCHEMBL13659026 | 0.79 | DGKA (0.55) | DGKALTA4HALDH1A1DNM1LMNA | |
| SCHEMBL7279379 | 0.78 | DGKA (0.48) | DGKAALDH1A1GLATOP2AADRA2A | |
| SCHEMBL21182396 | 0.77 | TSHR (0.54) | DGKALTA4HALDH1A1PAOXDNM1 | |
| SCHEMBL889250 | 0.77 | DGKA (0.48) | DGKALTA4HALDH1A1GLAPAOX | |
| SCHEMBL11511633 | 0.77 | GAA (0.48) | LTA4HALDH1A1TOP2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |