SCHEMBL8924930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14134508	0.91	POLB (0.57)	POLBKMT2AMEN1ALDH1A1RAB9A
	SCHEMBL14134390	0.91	POLB (0.57)	POLBKMT2AMEN1ALDH1A1RAB9A
	SCHEMBL14134499	0.91	POLB (0.57)	POLBKMT2AMEN1ALDH1A1RAB9A
	SCHEMBL12550524	0.91	ALDH1A1 (0.53)	KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL320116	0.89	POLB (0.59)	POLBKMT2AMEN1ALDH1A1RAB9A
	SCHEMBL11046065	0.83	ALDH1A1 (0.50)	KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2
	SCHEMBL21870620	0.82	HSD17B1 (0.54)	POLBKMT2AMEN1ALDH1A1RAB9A
	SCHEMBL28897183	0.82	POLB (0.49)	POLBKMT2AMEN1ALDH1A1SMN1; SMN2
	SCHEMBL14124746	0.81	POLB (0.52)	POLBKMT2AALDH1A1SMN1; SMN2CA12
	SCHEMBL14134501	0.81	POLB (0.52)	POLBKMT2AALDH1A1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.