Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341999 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL2880285 | 0.73 | BRD4 (0.38) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL17752757 | 0.71 | MAPT (0.43) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL6905998 | 0.69 | MAPT (0.45) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL2853994 | 0.69 | CYP3A4 (0.59) | ALDH1A1GAAMAPTKMT2ALMNA | |
| SCHEMBL598875 | 0.65 | NPC1 (0.46) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL3483012 | 0.65 | MAPT (0.36) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL3208997 | 0.65 | POLB (0.42) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL6985794 | 0.63 | GRIA1 (0.34) | — | |
| SCHEMBL10139767 | 0.62 | PNMT (0.37) | ALDH1A1MAPTNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696206-A | Method for preparing processable polyisothianaphthene | NATIONAL SCIENCE COUNCIL (TW) | 1997-12-09 | — | — | US | disclosed |
| US-5510457-A | Method for preparing processable polyisothianaphthene | NATIONAL SCIENCE COUNCIL (TW) | 1996-04-23 | — | — | US | disclosed |