Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.53 |
| ▸ | BCL2 | P10415 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129624 | 1.00 | PTPN1 (0.61) | PTPN1ITGB3ITGA2BITGA4BCL2 | |
| SCHEMBL8925517 | 0.92 | PTPN1 (0.66) | PTPN1ITGB3ITGA2BITGA4BCL2 | |
| SCHEMBL4417313 | 0.89 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4ITGB1 | |
| SCHEMBL1309887 | 0.89 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4ITGB1 | |
| SCHEMBL838170 | 0.89 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4ITGB1 | |
| SCHEMBL30962391 | 0.85 | CTSS (0.53) | PTPN1ITGB3ITGA2BACEITGB1 | |
| SCHEMBL193474 | 0.83 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL2891538 | 0.83 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL193473 | 0.83 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL11659351 | 0.83 | GPR34 (0.61) | PTPN1ITGB3ITGA2BBCL2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131343-A4 | HYDROPHILIC SOMATOSTATIN ANALOGS | ADMINISTRATORS OFTHE TULANE UN (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6465613-B1 | ADMINISTERING A SOMATOSTATIN DERIVATIVE TO A PATIENT FOR SELECTIVELY TARGETING AND ARRESTING THE GROWTH OF AN ANGIOGENIC BLOOD VESSEL OR A CELL | TULANE UNIVERSITY | 2002-10-15 | — | — | US | disclosed |
| EP-1131343-A1 | HYDROPHILIC SOMATOSTATIN ANALOGS | THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031122-A1 | HYDROPHILIC SOMATOSTATIN ANALOGS | TULANE UNIVERSITY (US) | 2000-06-02 | — | — | WO | disclosed |