Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988127 | 0.81 | SIGMAR1 (0.43) | FUCA1DRD2DRD3SIGMAR1GAA | |
| SCHEMBL9839788 | 0.79 | FUCA1 (0.41) | FUCA1DRD2DRD3SIGMAR1GAA | |
| Lithium Ion SCHEMBL9839786 | 0.78 | FUCA1 (0.40) | FUCA1DRD2DRD3SIGMAR1GAA | |
| SCHEMBL34473399 | 0.75 | FUCA1 (0.40) | FUCA1DRD2DRD3SIGMAR1TMEM97 | |
| SCHEMBL34474128 | 0.75 | FUCA1 (0.43) | FUCA1SIGMAR1TMEM97GAA | |
| SCHEMBL8924879 | 0.75 | OPRM1 (0.41) | FUCA1DRD2DRD3SIGMAR1 | |
| SCHEMBL7495999 | 0.70 | CHRM3 (0.39) | FUCA1SIGMAR1 | |
| SCHEMBL34474271 | 0.70 | ALDH1A1 (0.45) | FUCA1SIGMAR1TMEM97 | |
| SCHEMBL4482745 | 0.70 | FUCA1 (0.46) | FUCA1SIGMAR1GAA | |
| SCHEMBL31325224 | 0.70 | FUCA1 (0.46) | FUCA1SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621105-A | REACTING HALO-SUBSTITUTED QUINOLONECARBOXYLIC ACID OR NAPHTHYRIDONECARBOXYLIC ACID WITH 1-AMINOMETHYL-2-OXA-7-AZABICYCLO/3.3.0/OCTANE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5574161-A | GRAMPOSITIVE BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395944-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |