Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988127 | 0.97 | SIGMAR1 (0.43) | FUCA1SIGMAR1DRD2DRD3GAA | |
| Lithium Ion SCHEMBL9839786 | 0.93 | FUCA1 (0.40) | FUCA1SIGMAR1DRD2DRD3GAA | |
| SCHEMBL7510207 | 0.82 | SLC6A3 (0.44) | SIGMAR1DRD2ACHE | |
| SCHEMBL4482745 | 0.82 | FUCA1 (0.46) | FUCA1SIGMAR1GAAALDH1A1 | |
| SCHEMBL31325224 | 0.82 | FUCA1 (0.46) | FUCA1SIGMAR1GAAALDH1A1 | |
| SCHEMBL8925563 | 0.79 | FUCA1 (0.41) | FUCA1SIGMAR1DRD2DRD3GAA | |
| SCHEMBL11198892 | 0.76 | NR5A2 (0.46) | FUCA1GAAACHE | |
| SCHEMBL9183047 | 0.76 | OPRL1 (0.41) | FUCA1SIGMAR1GAAACHE | |
| SCHEMBL4237488 | 0.75 | GAA (0.54) | FUCA1SIGMAR1GAAACHE | |
| SCHEMBL1190231 | 0.75 | SIGMAR1 (0.46) | FUCA1SIGMAR1GAAARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002526-A1 | AZABICYCLO QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1991-03-07 | — | — | WO | disclosed |