Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767697 | 0.91 | PPARG (0.46) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8925558 | 0.85 | PPARA (0.40) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8767912 | 0.83 | SOAT1 (0.48) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8768932 | 0.81 | HDAC6 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8925426 | 0.81 | PPARA (0.45) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8924425 | 0.80 | PPARA (0.44) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8768853 | 0.80 | HDAC6 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8767877 | 0.78 | HDAC6 (0.59) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8767691 | 0.77 | PPARA (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8768643 | 0.77 | ALDH1A1 (0.46) | SOAT1PPARAPPARGEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |