Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.38 |
| ▸ | PRKCG | P05129 | 4/20 | 0.38 |
| ▸ | PRKCB | P05771 | 4/20 | 0.38 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | PRKCH | P24723 | 4/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 4/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 4/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925820 | 0.79 | CAMK2D (0.35) | CAMK2DPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8920200 | 0.68 | PRKCG (0.43) | CAMK2DPRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8653000 | 0.67 | PTPRC (0.40) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8919122 | 0.67 | PRKCB (0.43) | CAMK2DPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL22534426 | 0.66 | GSK3B (0.49) | PRKCAPTPRCCCNE2CDK4CCND1 | |
| SCHEMBL8923641 | 0.66 | CAMK2D (0.37) | CAMK2DPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8523454 | 0.65 | PTPRC (0.40) | CAMK2DPRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL8655119 | 0.65 | PRKD3 (0.41) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| Hydrochloric Acid SCHEMBL8654746 | 0.65 | PRKD3 (0.44) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8656527 | 0.65 | PTPRC (0.39) | PRKCGPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672618-A | TREATING DIABETIC COMPLICATIONS | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |