SCHEMBL8926029

SCHEMBL8926029

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)cc(C(=O)c3ccccc3)c1N2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALOX5 P09917 4/20 0.39
HSD17B10 Q99714 2/20 0.37
MAPT P10636 2/20 0.37
AURKA O14965 1/20 0.36
CNR2 P34972 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
NOX1 Q9Y5S8 1/20 0.35
HPGD P15428 3/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
SLC16A3 O15427 1/20 0.35
ALOX15 P16050 1/20 0.35
SLC16A1 P53985 1/20 0.35
ESRRG P62508 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8926638 0.90 MAOB (0.38) MAOBSMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL8926225 0.90 ESRRG (0.40) MAOBSMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL8926656 0.84 LMNA (0.40) SMN1; SMN2MEN1KMT2AL3MBTL1ALOX5
SCHEMBL9564335 0.84 MAOB (0.46) MAOBSMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL6260643 0.76 ALOX5 (0.39) SMN1; SMN2L3MBTL1ALOX5RAB9AHPGD
SCHEMBL80727 0.75 ALDH1A1 (0.44) MEN1KMT2AL3MBTL1ALOX5HSD17B10
SCHEMBL29895860 0.75 ALDH1A1 (0.44) MEN1KMT2AL3MBTL1ALOX5HSD17B10
SCHEMBL8759257 0.74 MAOB (0.36) MAOBSMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL7209657 0.74 MAPT (0.35) MEN1KMT2AL3MBTL1HSD17B10MAPT
SCHEMBL9215585 0.73 MEN1 (0.66) MAOBSMN1; SMN2MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663042-A LIGHT AND HEAT SENSITIVE SILVER HALIDE ELEMENNTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-02 US disclosed
EP-0681210-A1 Novel developing agents for (photo) thermographic systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-08 EP disclosed