Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531694 | 0.80 | LMNA (0.42) | CA2LMNATSHRNPSR1SMN1; SMN2 | |
| SCHEMBL531693 | 0.80 | LMNA (0.42) | CA2LMNATSHRNPSR1SMN1; SMN2 | |
| SCHEMBL2369273 | 0.80 | LMNA (0.42) | CA2LMNATSHRNPSR1SMN1; SMN2 | |
| SCHEMBL9852828 | 0.70 | CA2 (0.42) | CA2ALDH1A1HSD17B10TP53 | |
| SCHEMBL6982093 | 0.63 | HDAC8 (0.44) | CA2LMNAALDH1A1GAAPOLB | |
| SCHEMBL6977385 | 0.63 | MAOB (0.37) | DDB1CRBN | |
| SCHEMBL7417047 | 0.63 | GLA (0.66) | TSHRNPSR1HTT | |
| SCHEMBL13949518 | 0.63 | LMNA (0.38) | CA2LMNAALDH1A1HSD17B10NPSR1 | |
| SCHEMBL5872462 | 0.62 | HDAC8 (0.36) | CA2TSHRGAAPOLBCYP1A2 | |
| SCHEMBL31403360 | 0.62 | HDAC8 (0.36) | CA2TSHRGAAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9124621-A | — | — | None | — | — | JP | disclosed |
| JP-H09124621-A | OPTICALLY ACTIVE 1,3-OXAZOLIDINE-2-THIONE DERIVATIVE | SHIRATORI SEIYAKU KK | 1997-05-13 | — | — | JP | disclosed |