Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23477826 | 0.72 | POLB (0.42) | GBA1 | |
| SCHEMBL11315042 | 0.72 | ALDH1A1 (0.40) | GBA1ALDH1A1HSD17B10 | |
| SCHEMBL8145005 | 0.72 | HDAC8 (0.42) | CA2GBA1 | |
| SCHEMBL6979673 | 0.71 | GBA1 (0.37) | GBA1 | |
| SCHEMBL1558534 | 0.71 | GBA1 (0.48) | GBA1ALDH1A1 | |
| SCHEMBL6977385 | 0.70 | MAOB (0.37) | GBA1 | |
| SCHEMBL2369273 | 0.70 | LMNA (0.42) | CA2TP53 | |
| SCHEMBL8926068 | 0.70 | CA2 (0.37) | CA2ALDH1A1HSD17B10TP53 | |
| SCHEMBL23477892 | 0.70 | POLB (0.40) | GBA1ALDH1A1 | |
| SCHEMBL6982093 | 0.70 | HDAC8 (0.44) | CA2GBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451753-A1 | In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines | ASTA Medica Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |