Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ME2 | P23368 | 2/20 | 0.36 |
| ▸ | ME1 | P48163 | 2/20 | 0.36 |
| ▸ | ME3 | Q16798 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926249 | 0.90 | DGAT1 (0.51) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8931691 | 0.89 | DGAT1 (0.53) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8927419 | 0.88 | DGAT1 (0.47) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8931762 | 0.87 | DGAT1 (0.55) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8931712 | 0.86 | MAPT (0.54) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8931121 | 0.85 | DGAT1 (0.53) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7878336 | 0.85 | DGAT1 (0.53) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8931698 | 0.85 | DGAT1 (0.56) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8927569 | 0.85 | DGAT1 (0.53) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL8814915 | 0.85 | DGAT1 (0.51) | DGAT1MAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607932-A | Heterocyclic derivatives of azolones | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-03-04 | — | — | US | disclosed |