Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926837 | 0.85 | LMNA (0.38) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8597456 | 0.83 | TXNRD1 (0.42) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8629877 | 0.83 | LMNA (0.38) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8565650 | 0.82 | MGMT (0.50) | LMNAALDH1A1MAPTHTTMGMT | |
| SCHEMBL8596066 | 0.81 | NPY5R (0.43) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8598122 | 0.81 | TLR8 (0.48) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8925738 | 0.80 | GSK3A (0.39) | LMNAMAPTMEN1KMT2AMGMT | |
| SCHEMBL8627624 | 0.78 | MAPT (0.39) | LMNAALDH1A1GAAMAPTHTT | |
| SCHEMBL8625854 | 0.76 | CA2 (0.42) | TLR8LMNAALDH1A1GAAMAPT | |
| SCHEMBL8596810 | 0.76 | ALDH1A1 (0.47) | TLR8LMNAALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |