SCHEMBL8926797

SCHEMBL8926797

C=CC(=O)NC(=O)C(=O)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
PSMB11 A5LHX3 1/20 0.33
PSMA7 O14818 1/20 0.33
PSMB1 P20618 1/20 0.33
PSMA1 P25786 1/20 0.33
PSMA2 P25787 1/20 0.33
PSMA3 P25788 1/20 0.33
PSMA4 P25789 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB9 P28065 1/20 0.33
PSMA5 P28066 1/20 0.33
PSMB4 P28070 1/20 0.33
PSMB6 P28072 1/20 0.33
PSMB5 P28074 1/20 0.33
PSMB10 P40306 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10896387 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL7750969 0.77 TSHR (0.48) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL2932979 0.76
SCHEMBL20880332 0.74
SCHEMBL28161894 0.73 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL9452579 0.72 EGLN1 (0.46) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL1414999 0.71 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Hexane SCHEMBL9845035 0.71 ZDHHC20 (0.63) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL7165464 0.71
SCHEMBL26217 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP claimed
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US claimed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US claimed
US-5156718-A Made from kraft wood pulp, adjuvants and a binder of a conjugated diene, aromatic vinyl, acrylic and an activatable (hydrolizable) acrylic ester monomer; floor tiles; tensile strength GENCORP INC. (US) 1992-10-20 US claimed
EP-0470689-A1 Copolymer binders GENCORP INC. (US) 1992-02-12 EP claimed
EP-0426280-A1 Paper mats GENCORP INC. (US) 1991-05-08 EP claimed
US-4808660-A LOW TEMPERATURE CURABLE, TENSILE STRENGTH GENCORP INC. (US) 1989-02-28 US claimed
US-5629047-A IMPROVED TENSILE STRENGTH, LOW TEMPERATURE POLYMERIZATION GENCORP INC. (US) 1997-05-13 US disclosed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US disclosed
EP-0426280-B1 Paper mats GENCORP INC (US) 1994-08-31 EP disclosed
US-5274062-A An N-(substituted oxalyl)-halopropionamide NIPPON PAINT CO., LTD. (JP) 1993-12-28 US disclosed
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US disclosed
US-5166259-A Polymers for textiles on substrates GENCORP INC. (US) 1992-11-24 US disclosed
EP-0243208-A2 Acrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US disclosed
EP-0049910-B1 COPOLYMERS FORMED FROM ACTIVATED ESTER MONOMERS, AND COATING COMPOSITIONS CONTAINING SAID COPOLYMERS AMERICAN CYANAMID COMPANY (US) 1986-02-19 EP disclosed
EP-0020000-B1 ACTIVATED ESTER MONOMERS, POLYMERS FORMED THEREFROM AND COATING COMPOSITIONS CONTAINING SAID POLYMERS AMERICAN CYANAMID COMPANY (US) 1983-06-15 EP disclosed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed