Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927897 | 0.81 | LMNA (0.37) | L3MBTL1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL8927820 | 0.71 | MAPT (0.46) | L3MBTL1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL3043554 | 0.68 | GAA (0.50) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL17138214 | 0.68 | KDM4E (0.51) | GAAMAPTHPGDLMNAMEN1 | |
| SCHEMBL599254 | 0.67 | ADRA2A (0.35) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL30101193 | 0.67 | ADRA2A (0.35) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL13138537 | 0.66 | EGFR (0.47) | MEN1ALDH1A1KMT2A | |
| SCHEMBL12879334 | 0.66 | LMNA (0.49) | L3MBTL1GAALMNAALDH1A1KMT2A | |
| SCHEMBL791805 | 0.63 | LMNA (0.53) | LMNAALDH1A1 | |
| SCHEMBL11307754 | 0.62 | SMN1; SMN2 (0.56) | L3MBTL1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696151-A | Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-09 | — | — | US | disclosed |