Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138214 | 0.89 | KDM4E (0.51) | LMNAKDM4EALDH1A1MTNR1AKMT2A | |
| SCHEMBL12879338 | 0.84 | ACHE (0.46) | LMNAACHEALDH1A1KMT2AGAA | |
| SCHEMBL791805 | 0.82 | LMNA (0.53) | LMNAKDM4EALDH1A1MTNR1AMAOB | |
| SCHEMBL15800160 | 0.81 | ACHE (0.54) | LMNAACHEKDM4EKMT2AGAA | |
| SCHEMBL14540810 | 0.81 | CYP3A4 (0.58) | LMNAKDM4EALDH1A1MTNR1AKMT2A | |
| SCHEMBL19899163 | 0.79 | ACHE (0.52) | LMNAACHEKDM4EALDH1A1KMT2A | |
| SCHEMBL12105973 | 0.79 | AOC3 (0.43) | LMNAACHEALDH1A1KMT2AGAA | |
| SCHEMBL1135899 | 0.79 | NDUFS8 (0.49) | LMNAKDM4EALDH1A1MTNR1AKMT2A | |
| SCHEMBL18210782 | 0.79 | ALDH1A1 (0.46) | LMNAALDH1A1KMT2AGAAMAOB | |
| SCHEMBL1680484 | 0.78 | MAOB (0.45) | KDM4EALDH1A1MTNR1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-9326513-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-03 | — | — | US | disclosed |
| US-9326513-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-03 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-9096525-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-08-04 | — | — | US | disclosed |
| US-9045714-B2 | Dihydrobenzofuran derivatives as fragrance and/or flavoring materials | SYMRISE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9045714-B2 | Dihydrobenzofuran derivatives as fragrance and/or flavoring materials | SYMRISE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9045714-B2 | Dihydrobenzofuran derivatives as fragrance and/or flavoring materials | SYMRISE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| EP-2641903-A1 | Dihydrobenzofuran derivatives as olfactory and or aroma substances | Symrise AG (DE) | 2013-09-25 | — | — | EP | disclosed |
| US-20130243716-A1 | DIHYDROBENZOFURAN DERIVATIVES AS FRAGRANCE AND/OR FLAVORING MATERIALS | SYMRISE AG (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130243716-A1 | DIHYDROBENZOFURAN DERIVATIVES AS FRAGRANCE AND/OR FLAVORING MATERIALS | SYMRISE AG (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130243716-A1 | DIHYDROBENZOFURAN DERIVATIVES AS FRAGRANCE AND/OR FLAVORING MATERIALS | SYMRISE AG (DE) | 2013-09-19 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513286-B2 | Iminipyridine derivatives and their uses as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-20 | — | — | US | disclosed |
| WO-2012146125-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-11-01 | — | — | WO | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| WO-2008101682-A2 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046088-A1 | IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES | CD14, MYADM, MPO | LMNA 3752/4885ACHE 1503/4885KDM4E 3086/4885 |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | LMNA 3800/4885ACHE 45/4885KDM4E 577/4885 |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | LMNA 3800/4885ACHE 45/4885KDM4E 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.