Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7095854 | 0.85 | POLB (0.34) | POLBCYP1A2CYP3A4GAACYP2D6 | |
| Hydrochloric Acid SCHEMBL8927357 | 0.83 | HTR2A (0.32) | POLBCYP1A2CYP3A4GAACYP2D6 | |
| SCHEMBL8093928 | 0.79 | POLB (0.30) | POLB | |
| Hydrochloric Acid SCHEMBL2353823 | 0.71 | HTR2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL3783189 | 0.70 | HTR2A (0.35) | POLBCYP1A2CYP3A4GAACYP2D6 | |
| SCHEMBL8366223 | 0.68 | POLB (0.35) | POLBCYP1A2CYP3A4GAACYP2D6 | |
| SCHEMBL7600618 | 0.67 | POLB (0.38) | POLB | |
| Hydrochloric Acid SCHEMBL7592112 | 0.67 | POLB (0.34) | POLB | |
| Bromide SCHEMBL7205884 | 0.67 | HTR2A (0.35) | POLB | |
| SCHEMBL10455248 | 0.66 | POLB (0.33) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | claimed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |