Zinc Ion

Zinc Ion

SCHEMBL8927458

CC(=O)Oc1c(C(=O)[O-])ccc2ccccc12.CC(=O)Oc1c(C(=O)[O-])ccc2ccccc12.CC(=O)Oc1cc2ccccc2cc1C(=O)[O-].CC(=O)Oc1cc2ccccc2cc1C(=O)[O-].[Zn+2].[Zn+2]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.45
MAPT P10636 3/20 0.43
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 5/20 0.41
GAA P10253 3/20 0.41
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 2/20 0.41
BLM P54132 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
NCEH1 Q6PIU2 1/20 0.37
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL536340 0.91 HPGD (0.43) HTTMAPTMAPK1KDM4EGAA
Zinc Ion SCHEMBL536583 0.86 MAPT (0.50) HTTMAPTMAPK1KDM4EGAA
SCHEMBL6621295 0.77 HPGD (0.46) HTTMAPTMAPK1KDM4EGAA
SCHEMBL2761576 0.76 WDR5 (0.56) HTTMAPTMAPK1KDM4EGAA
SCHEMBL9488962 0.76 HTT (0.54) HTTMAPTMAPK1KDM4EGAA
SCHEMBL536341 0.75 WDR5 (0.54) HTTMAPTMAPK1KDM4EGAA
SCHEMBL8582319 0.74 KDM4E (0.59) HTTMAPTMAPK1KDM4EGAA
Zinc Ion SCHEMBL536405 0.74 NCEH1 (0.55) HTTMAPK1KDM4EGAAALDH1A1
SCHEMBL615984 0.73 KDM4E (0.69) MAPTMAPK1KDM4EGAAALDH1A1
SCHEMBL6906339 0.72 CA12 (0.55) HTTMAPTMAPK1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5622909-A DEVELOPER LAYER COMPRISING LEUCO DYE, PHTHALIC ACID DERIVATIVE; STORAGE STABILITY RICOH COMPANY, LTD. (JP) 1997-04-22 US disclosed