SCHEMBL8927729

SCHEMBL8927729

CNC(=O)Oc1ccccc1C

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
PGR P06401 1/20 0.61
GAA P10253 1/20 0.61
PTGS1 P23219 1/20 0.61
MAPK1 P28482 1/20 0.61
HSD17B10 Q99714 1/20 0.61
ACHE P22303 1/20 0.61
CYP1A2 P05177 1/20 0.47
LMNA P02545 1/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PPARG P37231 1/20 0.45
BCHE P06276 1/20 0.45
NOTUM Q6P988 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30989358 0.85 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL5191682 0.85 ALDH1A1 (0.57) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL9324445 0.80 ALDH1A1 (0.66) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL92889 0.80 ALDH1A1 (0.61) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL25295423 0.79 ATM (0.42) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL14069318 0.79 NPSR1 (0.50) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL25275004 0.79 L3MBTL1 (0.58) GAAACHELMNAATMTDP1
SCHEMBL8048675 0.79 NOTUM (0.59) ALDH1A1GAAATMNOTUM
SCHEMBL7064558 0.79 TDP1 (0.50) LMNAATMTDP1L3MBTL1PPARG
SCHEMBL236664 0.79 TDP1 (0.50) ALDH1A1HSD17B10LMNAATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877365-A1 SUBSTITUTED TOLYL AS FUNGICIDES FMC CORPORATION (US) 2021-09-15 EP claimed
CN-110698416-B Preparation method of pyridine quinazoline intermediate 湖南速博生物技术有限公司 2020-03-20 CN claimed
CN-110698416-A Preparation method of pyridine quinazoline intermediate 湖南速博生物技术有限公司 2020-01-17 CN claimed
CN-103562198-B There is muscarinic receptor antagonist and the compound of beta 2-adrenergic receptor agonists activity 奇斯药制品公司 2016-08-24 CN claimed
EP-2912020-A1 SUBSTITUTED TOLYL FUNGICIDES E. I. du Pont de Nemours and Company (US) 2015-09-02 EP claimed
WO-2014066120-A1 SUBSTITUTED TOLYL FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-05-01 WO claimed
CN-103562198-A Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity CHIESI FARMA SPA 2014-02-05 CN claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-107434774-B Method for synthesizing diphenylmethane dicarbamic acid ester from phenyl carbamate 中国石油化工股份有限公司 2020-06-02 CN disclosed
CN-110698416-B Preparation method of pyridine quinazoline intermediate 湖南速博生物技术有限公司 2020-03-20 CN disclosed
CN-110698416-A Preparation method of pyridine quinazoline intermediate 湖南速博生物技术有限公司 2020-01-17 CN disclosed
EP-3495353-A1 AMIDATE COMPOUND, CATALYST FOR POLYURETHANE PRODUCTION, AND METHOD FOR PRODUCING POLYURETHANE RESIN Koei Chemical Company, Limited (JP) 2019-06-12 EP disclosed
EP-0190466-B1 PROCESS FOR THE PRODUCTION OF N-METHYLCARBAMATES ENICHEM SYNTHESIS S.p.A. (IT) 1990-11-28 EP disclosed
CN-1004353-B Process for preparing N-methyl carbamates 埃尼凯姆·辛泰希公司 1989-05-31 CN disclosed
US-4692550-A Continuous process for thermal splitting of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4659845-A Process for the production of N-methylcarbamates ENICHEM SINTESI S.P.A. (IT) 1987-04-21 US disclosed
CN-85109417-A The preparation method of N-methyl carbamate class 1986-12-03 CN disclosed
US-4609648-A SYNERGISTS FOR ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-09-02 US disclosed
US-3938986-A ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed